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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
MPT0B390 is an arylsulfonamide-based derivative that exhibits potent HDAC inhibitory ability. It acts as a TIMP3 inducer and is shown to inhibit tumor growth, metastasis, and angiogenesis. This compound demonstrates antiproliferative activity against the human colon cancer cell line HCT116 with a GI50 of 0.03 μM.
Exhibits potent HDAC inhibitory ability
Acts as a TIMP3 inducer
Inhibits tumor growth, metastasis, and angiogenesis
Demonstrates antiproliferative activity against human colon cancer cell line HCT116 with a GI50 of 0.03 μM
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Laflunimus is an immunosuppressive research compound and an analogue of the leflunomide-active metabolite A77 1726. It functions as an orally active inhibitor of dihydroorotate dehydrogenase (DHODH) and also inhibits prostaglandin endoperoxide H synthase (PGHS)-1 and -2; it suppresses immunoglobulin secretion with low micromolar potency.
High purity suitable for research applications.
Inhibits DHODH for studies of pyrimidine synthesis and immunomodulation.
Suppresses IgM and IgG secretion at low micromolar concentrations.
Also inhibits PGHS-1 and PGHS-2, supporting inflammation pathway research.
Available as solid and as a solution for flexible experimental use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More